Mlac : ICR

  • Sciencetific Name : Mus musculus
  • Strain : ICR
  • Source : Japan (1980)
  • Coat color : Albino

Biological Data

  • Adult body weight : Male 25-40 grams, Female 20-35 grams
  • Average life span : 2-2.5 years
  • Age at mating : Male 6-8 weeks (25-40 grams),
    Female 6-8 weeks (25-35 grams)
  • Estrous : 4-5 days
  • Duration of estrus : 10 hours
  • Reproductive time : 8-9 months
  • Gestation period : 19-21 days
  • Weaning age : 18-21 days (10-14 grams)
  • Litter size : 1-1.5 pups (average 4)
  • Narmal birth weight : 1-1.5 grams
  • Post partum estrus : - NO -
  • Food consumption : 3-6 grams/animal/day (Adult)
  • Water consumption : 3-8 ml./animal/day (Adult)
  • Nipples : 10, 3 Pairs on the thorax, 2 Pairs on the abdomen.
  • Eyes open : 12 days

Growth rate

Husbandry

 1. Husbandry

      Breeding Systems
                    Maximum avoidence of inbreeding is used for stock maintenance system infoundation stock and random mating system is used for production in production stock.

      Environment
                   The Mlac:ICR is housed in controlled environment. The ventilation, temperature and humidity are controlled by HVAC (Heating, Ventilating, Air conditioning) system.
                  – Temperature range is controlled at about 22 ± 2 ํC
                  – Relative humidity range at about 55 + 10%
                  – Air changes per hour at 15-20 ACH
                  – Light: dark cycle is adjusted at 12:12 hours
                  – Mouse are sensitive to noise so the noise level should be maintained at< 85 db.

       Feed and water
                  The Mlac:ICR is fed on the commercial diet (No. 082) product of Perfect companion group co. Ltd., the animal feed manufacturer which milled according to our requested specifications. Food is provided in stainless steel wire- bar lid feeders ad libitum. The RO Water is used for the drinking water which is chlorinated at a concentration of 5-6 ppm to make it free from Pseudomonas aeruginosa. The drinking water is provided in bottles with sipper tubes.

       Bedding
                    Dried water hyacinth and corn cob are is used for mouse as bedding material. The same bedding is used in shipping containers. Dried bedding is packed in 3 Layers paper bags and sterilized by autoclave at 135 ํC for 7 minutes before used.

Equipment

Different size of cages are used in different breeding processes as follows.

Dimensions of Enclosure (W×L×H)(centimeter) Maximum Number Animals/Enclosure Types of Enclosure & Description
7.5 × 11.5 × 5 6 animals/cage (or) 1 animal (lactating female)/cage Polysulfonate and stainless steel cages with stainless steel wire-bar lids
11 × 18× 6 4 Female + litter (lactating female)/cage Stainless steel shoe box type with stainless wire-bar lid
14 × 29× 6 8 Female + litter (lactating female)/cage Stainless steel shoe box type with stainless wire-bar lid
14 × 29× 6 35 animals(5-8 weeks)/cage
50 animals(3-4 weeks)/cage
Stainless steel shoe box type with stainless wire-bar lid

Space requirement for Mlac:ICR.

Weight, g. Floor Area/Animal,(in2) Height/inches
Under 10 6 5
Up to 15 8 5
Up to 25 12 5
Over 25 At least 15 5

 Click here for more information of  “Inbred Strain / Outbred Stock”