ICR/Mlac-Hydro

Adult body weight   ::  Male 25-40 grams,Female 20-35 grams.
Average life span  ::  2-2.5 years.
Age at mating  ::  Male 6-8 weeks (25-40 grams) , Female 6-8 weeks (25-35 grams)
Estrous cycle   ::  4-5 days
Duration of estrus   ::  10 hours
Reproductive time   ::  8-9 months
Gestation period   ::  19-21 days
Weaning age   ::   19-21 days (10-14 grams)
Litter size   ::   1-14 pups (average 7)
Normal birth weight   ::  1-1.5 grams
Post partum estrus   ::  – NO –
Food consumption   ::  3-6 grams /animal/day (Adult)
Water consumption   ::  3-8 ml/animal/day (Adult)
Nipples   ::  10,3 Pairs on the thorax, 2 Pairs on the abdomen.
Eyes open   ::  12 days
Incidence of Hydonephrosis  ::   100% positive in both sex
Severity   ::  Incidence of servere hydronephrosis in both sides of kidney

Breeding Systems

Inbred for 26 generations +. Hydronephrosis mice are maintained in brother/sister mating system.

Environment

The ICR hydronephrosis mouse is housed in the controlled environment. The ventilation, temperature and humidity are controlled by HVAC (Heating, Ventilating, Air conditioning) system.

– Temperature range at about 24 ± 2 ํC
– Relative humidity is ranged between 55 + 10%
– Air changes per hour 10-15 ACH
– Light: and dark cycle 12:12 hours
– Mouse is sensitive to noise so the noise level should be < 85 db.

Feed and water

The ICR hydronephrosis mouse is fed on the commercial diet (No. CP 082) product of Perfect companion group co. Ltd. which milled according to our requested specifications. Food is provided ad libitum in stainless steel wire- bar lid feeders. The chlorinated RO Water is used for the drinking water. 10-12 ppm chlorination make the water free from Pseudomonas aeruginosa. Drinking water is provided in bottles with sipper tubes.

Bedding

Hard wood chips (or shaving) is used for mouse as bedding material. The same bedding is used in shipping containers. Dried bedding is packed in brown paper bags and sterilized by autoclave at 135 C for 7 minutes before used.

 Click here for more information of  “Inbred Strain / Outbred Stock”