Scientific name : Mus Musculus
Strain : ICR Hydronephrosis Inbred mouse
Source : National Laboratory Animal Center established since (1992)
Coat color : Albino
Biological Data :: Adult body weight
Male :: 25-40 grams,Female 20-35 grams.
Average life span :: 2-2.5 years.
Age at mating :: Male 6-8 weeks (25-40 grams) , Female 6-8 weeks (25-35 grams)
Estrous cycle : 4-5 days
Duration of estrus 10 hours
Reproductive time 8-9 months
Gestation period 19-21 days
Weaning age 19-21 days (10-14 grams)
Litter size 1-14 pups (average 7)
Normal birth weight 1-1.5 grams
Post partum estrus – NO –
Food consumption 3-6 grams/animal/day (Adult)
Water consumption
3-8 ml/animal/day (Adult)
Nipples 10,3 Pairs on the thorax, 2 Pairs on the abdomen.
Eyes open 12 days
Breeding Systems
Brother-syster selective mating system is used to maintain ICR Free hydronephrosis mouse in foundation stock.
Environment
The ICR hydronephrosis mouse is housed in the controlled environment. The ventilation, temperature and humidity are controlled by HVAC (Heating, Ventilating, Air conditioning) system.
– Temperature range at about 24 ± 2 ํC
– Relative humidity is ranged between 55 + 10%
– Air changes per hour 10-15 ACH
– Light: and dark cycle 12:12 hours
– Mouse is sensitive to noise so the noise level should be < 85 db.
Feed and water
The Mlac:ICR is fed on the commercial diet (No. CP 082) product of Perfect companion group co. Ltd., the animal feed manufacturer which milled according to our requested specifications. Food is provided in stainless steel wire- bar lid feeders ad libitum. The RO Water is used for the drinking water which is chlorinated at a concentration of 10-12 ppm to make it free from Pseudomonas aeruginosa. The drinkingwater is provided in bottles with sipper tubes
Bedding
Hard wood chips (or shaving) is used for mouse as bedding material. The same bedding is used in shipping containers. Dried bedding is packed in brown paper bags and sterilized by autoclave at 135 C for 7 minutes before used.
| Dimensions of Enclosure (W×L×H)(centimeter) | Maximum Number Animals/Enclosure | Types of Enclosure & Description |
|---|---|---|
| 7.5 × 11.5 × 5 | 6 animals/cage (or) 1 animal (lactating female)/cage |
Polysulfonate cages and stainless steel cages with stainless steel wire-bar lid |
Experimental Uses
The genetic background of this strain is similar to ICR Outbred mouse strain of our Center but they are totally free from hydronephrosis mutant gene.
Click here for more information of “Inbred Strain / Outbred Stock”
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